(Z)-3,5,4'-Trimethoxystilbene
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基本情報
- CAS
94608-23-8- 標準SMILES
COc1ccc(/C=C\c2cc(OC)cc(OC)c2)cc1- InChIKey
GDHNBPHYVRHYCC-PLNGDYQASA-N- 分子式
- C17H18O3
- 平均分子量
- 270.32 g/mol
- 単同位体質量
- 270.12559443
名称と識別子
- 優先名称
- (Z)-3,5,4'-Trimethoxystilbene
- IUPAC
- 1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]benzene
- 英語名
- CIS-TRIMETHOXY STILBENE
- 分子式
- C17H18O3
- 分子量
- 270.32
名称と別名
94608-23-8(Z)-3,5,4'-TRIMETHOXYSTILBENEV36C3MR96BDTXSID5013069333,5,4'-Trimethoxystilbene, (Z)-RefChem:1051259DTXCID001736882cis-trismethoxy Resveratrol1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]benzeneCHEMBL3116361,3-dimethoxy-5-[(1Z)-2-(4-methoxyphenyl)ethenyl]benzenecis-trismethoxy Resveratrol (Solution in Ethanol)
名称をさらに表示
CIS-TRIMETHOXY STILBENE USP/EP/BPResveratrol Trimethyl Ether cis-Isomercis-trismethoxy Resveratrol, 10 mM in DMSO1,2,3-trimethoxy-4-(2-phenylethenyl)benzeneResveratrol Impurity 27 (cis-trismethoxy Resveratrol)(Z)-1-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)ethene
CIS-TRIMETHOXY STILBENEcis-Trismethoxyresveratrolcis-Stilbene Derivative, 5aorb1304317SCHEMBL10062078Z-3,4',5-trimethoxystilbeneBDBM239401,3-Dimethoxy-5-[(Z)-2-(4-methoxyphenyl)vinyl]benzene
データベース識別子
- CAS
94608-23-8- PubChem CID
- 9878556
- DTXSID
DTXSID501306933- ChEMBL
CHEMBL311636- UNII
- V36C3MR96B
- Nikkaji
- J490.040E
物性
構造計算による物性補完中
- XLogP
- 4.1
- 極性表面積
- 27.7 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 3
- 回転可能結合数
- 5
- 重原子数
- 20
- 形式電荷
- 0
- 複雑度
- 283
物理化学的性質
- 融点
- 55 · 55-57 °C
- 沸点
- 423.8 · 423.8±35.0 °C(Predicted)
- 比重(密度)
- 1.104 · 1.104±0.06 g/cm3(Predicted)
- 貯蔵温度
- -20 °C · Store at -20°C
- 溶解性
- 50 mg/ml · ≤50mg/ml in DMSO;50mg/ml in dimethyl formamide
- 外見
- solution in ethanol.
- 色
- Colorless to light yellow
- CAS データベース
- 94608 · 94608-23-8
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
安全データ
- risk_code
- 41
- hazard_code
- Xi
- safety_code
- 26-39
化学と産業
応用分野
説明Resveratrol is a potent antioxidant found in grapes and red wine that also has anti-proliferative, anti-neoplastic and anti-angiogenic activities. In addition, resveratrol activates sirtuins and, in yeast, extends lifespan. cis-trismethoxy Resveratrol is a potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells. It inhibits tubulin polymerization in a dose-dependent manner (IC50 = 4 μM) and inhibits enzymes involved in the synthesis of the polyamines, putrescine, and spermidine. trans-trismethoxy Resveratrol has superior pharmacokinetic characteristics when compared with resveratrol, including greater plasma exposure, longer elimination half-life, and lower clearance.
使用Resveratrol is a potent antioxidant found in grapes and red wine that also has anti-proliferative, anti-neoplastic and anti-angiogenic activities. In addition, resveratrol activates sirtuins and, in yeast, extends lifespan. cis-trismethoxy Resveratrol is a potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells. It inhibits tubulin polymerization in a dose-dependent manner (IC50 = 4 μM) and inhibits enzymes involved in the synthesis of the polyamines, putrescine, and spermidine. trans-trismethoxy Resveratrol has superior pharmacokinetic characteristics when compared with resveratrol, including greater plasma exposure, longer elimination half-life, and lower clearance.
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