Hexafluoropropylene oxide (HCID 9883)

概要

Hexafluoropropylene oxide is a colorless odorless gas. It is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Its vapors are heavier than air. It can cause asphyxiation by the displacement of air. Exposure of the container to prolonged heat or fire may cause it to rupture violently and rocket.

名称と識別子

優先名称: Hexafluoropropylene oxide
IUPAC: 2,2,3-trifluoro-3-(trifluoromethyl)oxirane
現地名: 1,1,2,3,3,3-ヘキサフルオロ-1,2-エポキシプロパン
英語名: Hexafluoropropylene oxide
分子式: C3F6O
分子量: 166.02

名称と別名

Hexafluoropropylene oxide428-59-1Hexafluoropropene oxide2,2,3-Trifluoro-3-(trifluoromethyl)oxiraneHfpoTRIFLUORO(TRIFLUOROMETHYL)OXIRANEPerfluoropropylene oxideHexafluoro-1,2-epoxypropaneHexafluoropropene epoxideHexafluoropropylene epoxideHexafluoroepoxypropanePropylene oxide hexafluoride

名称をさらに表示

2,3,3-トリフルオロ-2-(トリフルオロメチル)オキシラン1,1,2,3,3,3-ヘキサフルオロ-1,2-エポキシプロパンヘキサフルオロプロピレンオキシド2,3,3-トリフルオロ-2-トリフルオロメチルオキシラン2-(トリフルオロメチル)-2,3,3-トリフルオロオキシラン2-(トリフルオロメチル)トリフルオロオキシラン2,2,3-トリフルオロ-3-(トリフルオロメチル)オキシランヘキサフルオロプロピレンエポキシド1,2-エポキシヘキサフルオロプロパンヘキサフルオロプロピレンオキサイド1,1,2,3,3,3-Hexafluoro-1,2-epoxypropaneC3F6ONA 1956(S) TRIMETHYLOXIRANE

Oxirane, trifluoro(trifluoromethyl)-JPY12AP87NPropane, 1,2-epoxy-1,1,2,3,3,3-hexafluoro-RefChem:146014ACETONE, HEXAFLUOROHFPO hexafluoropropylene oxide207-050-4Poly(perfluoropropyleneoxide)

データベース識別子

CAS: 428-59-1
PubChem CID: 9883
DTXSID: DTXSID6029177
UNII: JPY12AP87N
EC Number: 207-050-4
Nikkaji: J27.198E

物性

構造計算による物性

XLogP: 2.1
極性表面積: 12.5 Å²
水素結合供与体数: 0
水素結合受容体数: 7
回転可能結合数: 0
重原子数: 10
形式電荷: 0
複雑度: 161

実験および物理化学的性質

PFAS · 6 件

PFAS -> OECD Category

PFAS -> Suspected persistent, mobile, toxic (PMT) PFAS or PFAS-like compounds

PFAS

PFAS -> Intentionally added food contact chemicals

PFAS -> PFAS identified in REACH Regulation EC No. 1272/2008

PFAS -> Other/unspecified

PolymersPlastics & Rubber -> Other Monomers

Boiling Point-18 °F at 760 mmHg (NTP, 1992)

Decomposition · 1 件

AT TEMP BETWEEN 500-800 °C, CARBONYL FLUORIDE (COF2) IS DOMINANT PYROLYSIS PRODUCT. THIS GAS IS VERY SUSCEPTIBLE TO HYDROLYSIS, READILY YIELDING HYDROFLUORIC ACID & CARBON DIOXIDE. ABOVE 800 °C, THE PYROLYSIS PRODUCTS CONSIST OF INORGANIC FLUORIDE, A LITTLE TETRAFLUOROMETHANE & CARBON DIOXIDE. /POLYFLUORINES/

Melting Point-200 °F (NTP, 1992)

Physical Description · 3 件

Hexafluoropropylene oxide is a colorless odorless gas. It is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Its vapors are heavier than air. It can cause asphyxiation by the displacement of air. Exposure of the container to prolonged heat or fire may cause it to rupture violently and rocket.

Gas Vapor; CBI; Liquid

Colorless odorless gas; Shipped liquefied under its vapor pressure; [CAMEO]

物理化学的性質

融点: -129 °C · -129°C
沸点: 42 °C · −42 °C(lit.)
比重(密度): 1.67 · 1.67±0.1 g/cm3(Predicted)
蒸気圧: 680.85 kPa · 680.85kPa at 25℃
水溶解度: 16.3 μg/L · 16.3μg/L at 22.7℃
Henry's Law Constant: 9.3 · 9.3×10-6 mol/(m3Pa) at 25℃, Clever et al. (2005)
InChI: InChI=1S/C3F6O/c4-1(2(5,6)7)3(8,9)10-1
InChIKey: PGFXOWRDDHCDTE-UHFFFAOYSA-N
SMILES: O1C(F)(C(F)(F)F)C1(F)F
LogP: 1.72 at · 1.72 at 25℃
CAS データベース: 428 · 428-59-1(CAS DataBase Reference)
NISTの化学物質情報: Oxirane, trifluoro(trifluoromethyl)-(428-59-1)
EPAの化学物質情報: 2 · Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- (428-59-1)

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 24.2% (16 of 66) of reports.

Danger

H280 (74.2%): Contains gas under pressure; may explode if heated [Warning Gases under pressure]

P260, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P410+P403, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 66 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

危険有害性情報

Regulatory Information · 4 件

Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

S - indicates a substance that is identified in a final Significant New Use Rule.

Status: Active Update: 21-01-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/5721

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelNon-Flammable Gas

Fire HazardsExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Health HazardsExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Hazards Summary · 1 件

May polymerize; Containers may explode from prolonged heat; Evaporating liquid can cause frostbite; In confined space spill, may displace air and act as simple asphyxiant; [CAMEO] May explode if heated under confinement; An irritant; In confined space spill, may displace air and act as simple asphyxiant; [MSDSonline]

Reactive GroupEpoxides

安全と保護具

Fire FightingExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill ResponseExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Preventive Measures · 1 件

VENTILATION CONTROL: ...WHERE...RESINS ARE LIKELY TO UNDERGO PYROLYSIS & DECOMP DURING PROCESSING, PROVISION SHOULD BE MADE FOR ADEQUATE LOCAL EXHAUST & GENERAL VENTILATION TO KEEP CONCN OF DECOMP PRODUCTS AS LOW AS POSSIBLE. /POLYFLUORINES/

Isolation and EvacuationExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Personal Protective Equipment (PPE)Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

毒性情報

Adverse EffectsOther Poison - Simple Asphyxiant

Human Toxicity Excerpts · 1 件

A UNIQUE EFFECT FROM PYROLYSIS PRODUCTS OF PTFE /POLYTETRAFLUOROETHYLENE/ RESINS...BEEN OBSERVED IN MAN... THIS IS AN INFLUENZA-LIKE SYNDROME RESEMBLING METAL FUME FEVER & HAS BEEN TERMED "POLYMER FUME FEVER". IT IS SELF-LIMITING, LASTS...24-48 HR & REQUIRES ONLY SYMPTOMATIC TREATMENT. /POLYFLUORINES/

Non-Human Toxicity Excerpts · 1 件

IN ACUTE STUDIES WITH MICE & RATS IT CAUSED CHANGES IN LIVER & KIDNEY. IN SPLEEN IT CAUSED VASCULAR PERMEABILITY & DEGENERATIVE DYSTROPHIC CHANGES & INFLAMMATION. EXTENT & NATURE OF TOXICITY DEPENDS UPON TYPE OF METABOLITES THAT ARE PRODUCED.

Probable Routes of Human Exposure · 1 件

A UNIQUE EFFECT FROM PYROLYSIS PRODUCTS OF PTFE /POLYTETRAFLUOROETHYLENE/ RESINS...BEEN OBSERVED IN MAN... THIS IS AN INFLUENZA-LIKE SYNDROME RESEMBLING METAL FUME FEVER & HAS BEEN TERMED "POLYMER FUME FEVER". IT IS SELF-LIMITING, LASTS...24-48 HR & REQUIRES ONLY SYMPTOMATIC TREATMENT. /POLYFLUORINES/

安全データ

wgk: 3
tsca: TSCA listed
ridadr: UN 1956 2.2
risk_code: 36/37/38-44
化審法: 新規公示化学物質（2011年3月31日以前届出）
hazard_code: Xi
hazard_note: Irritant
safety_code: 7-26-37/39-38
hazard_class: 2.2
有毒物質データの: 428-59-1(Hazardous Substances Data)

化学と産業

用途と製造

Uses · 2 件

Used as monomer for heat-resistant hexafluoropropylene oxide polymers; [HSDB]

MONOMER FOR HEXAFLUOROPROPYLENE OXIDE POLYMERS THAT ARE HEAT RESISTANT TO 410 °C

U.S. Production2023: 2,500,000 - <4,000,000 lb

Industry UsesIntermediate

Methods of ManufacturingOXIDATION OF HEXAFLUOROPROPYLENE WITH ALKALINE HYDROGEN PEROXIDE...ABOUT -30 °C.

Use ClassificationPFAS (per- and polyfluoroalkyl substances) -> OECD Category

General Manufacturing Information · 4 件

All Other Basic Organic Chemical Manufacturing

Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)-: ACTIVE

"FREON E" /IS/ TRADEMARK FOR SERIES OF HYDROGEN END-CAPPED TETRAFLUOROETHYLENE EPOXIDE POLYMERS HAVING A DP /DEGREE OF POLYMERIZATION/ UP TO 10. BOILING RANGE 39-490 °C. HIGH DIELECTRIC CONSTANT. USED AS COOLANTS IN ELECTRONIC DEVICES. /FREON E/

"KRYTOX" /IS/ TRADEMARK FOR A SERIES OF HEXAFLUOROPROPYLENE EPOXIDE POLYMERS OF MEDIUM MOLECULAR WT, USED AS LUBRICATING OILS & GREASES. FOR USE IN HIGH TEMP OR CORROSIVE CONDITIONS; GOOD CHEM INERTNESS, EVEN WITH BOILING SULFURIC ACID; LOW SOLUBILITY IN MOST SOLVENTS; GOOD LUBRICITY UNDER LOAD... /KRYTOX/

応用分野 · 2 件

使用Hexafluoropropylene oxide is an important intermediate of organic fluorine material.HFPO is mainly used in the manufacture of high-quality fluorinated compounds.It is the main component of perfluor-vinyl ether(PPVE,PSVE,PFVE,PMVE) and the monomer of fluorinated surfactants and fluorinated ether oil.

一般的な説明Hexafluoropropylene oxide is a colorless odorless gas. Hexafluoropropylene oxide is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Its vapors are heavier than air. Hexafluoropropylene oxide can cause asphyxiation by the displacement of air. Exposure of the container to prolonged heat or fire may cause Hexafluoropropylene oxide to rupture violently and rocket.