Hydrochloric Acid → 12-Aminododecyl methanesulfonate hydrochloride
反応式
[S:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18]C(=O)OC(C)(C)C)([CH3:4])(=[O:3])=[O:2].[ClH:26].CCCCCC>C(OCC)(=O)C>[ClH:26].[CH3:4][S:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH2:18])(=[O:3])=[O:2]参加物
5
実験手順
To a solution of 8.06 g of tert-butyl N-(12-mesyloxydodecyl)carbamate in 60 ml of ethyl acetate was added 10 ml of hydrochloric acid under ice-cooling and the mixture was stirred at room temperature for one hour. The reaction solution was cooled with ice, hexane was added, the crystal thus precipitated out was recovered by filtration and dried under reduced pressure to afford the title compound.