4-Methyl-5-[3-[(tetrahydropyran-2-yl)oxy]propyl]pyrrolidin-2-one → 5-(3-Hydroxypropyl)-4-methylpyrrolidin-2-one
反応式
[CH3:1][CH:2]1[CH:6]([CH2:7][CH2:8][CH2:9][O:10]C2CCCCO2)[NH:5][C:4](=[O:17])[CH2:3]1>C(O)(=O)C.C1COCC1.O>[OH:10][CH2:9][CH2:8][CH2:7][CH:6]1[NH:5][C:4](=[O:17])[CH2:3][CH:2]1[CH3:1]参加物
3
実験手順
A mixture of the title compound of EXAMPLE 234 is treated with acetic acid:THF:water (4:2:1), and concentrated. The resulting material is purified by column chromatography to yield the title material.
後処理
- concentrationconcentrated
- customThe resulting material is purified by column chromatography
出典と根拠
- ORDレコード
- ord-9501bf8704d647cb87e88a48261965dd
- 出典データセット
- uspto-grants-2000_04
- 特許番号
- US06046211
反応ノート
読み込み中…