反応式
C(O)(=O)C.N=C1CC(C)CCN1.[NH2:13][C:14]1[C:19]([Cl:20])=[CH:18][C:17]([C:21]([F:24])([F:23])[F:22])=[CH:16][N:15]=1>>[ClH:20].[NH:13]=[C:14]1[CH2:19][CH2:18][CH:17]([C:21]([F:23])([F:22])[F:24])[CH2:16][NH:15]1参加物
3
実験手順
The method of preparation of 2-imino-4-methylpiperidine acetate was used to convert 2-amino-3-chloro-5-(trifluoromethyl)pyridine to the title compound except platinum oxide was used as the catalyst. Product was triterated with ether to give a white solid. The analysis of the product was found to be consistent with the proposed structure. MH+=167; 1H NMR (D2O): δ3.65-3.50 (m, 1H); 3.40-3.20 (m, 1H); 2.85-2.45 (m, 3H); 2.15-2.00 (m, 1H); 1.80-1.60 (m, 1H).
出典と根拠
- ORDレコード
- ord-f73f74a74d7945ce9a37e3a9054008a4
- 出典データセット
- uspto-grants-2000_04
- 特許番号
- US06046211
関連ノート
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