化工社化工社 化学情報印刷レポート · 研究参考用
Acetyl chloride → N-Methyl-phenylglycine methyl ester hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetyl chloride | HCID 6367 | — |
| 反応物 | N-Methyl-N-phenyl-glycine | HCID 420843 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | N-Methyl-phenylglycine methyl ester hydrochloride | HCID 70291077 | 94% |
反応手順
Prepared by Method A of Example 19 but using N-methyl-phenylglycine (prepared in turn from 2-chlorophenylacetic acid and methylamine) (3.5 g) methanol (20 ml) and acetyl chloride (40 ml) over 48 hours. The title compound was obtained in 94% yield, after trituration with methanol, as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06048852 |
| 出典データセット | uspto-grants-2000_04 |
| ORD ID | ord-3f0ae84401de4753b2d31985f3ef5bd9 |
| 出典メモ | uspto-grants-2000_04 |