Methylhydrazine → 4-Chlorobenzaldehyde (N-methyl)hydrazone

HRID 1005275

反応式

HRID 1005275 の反応式
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[CH3:10][NH:11][NH2:12]>C(O)C>[CH3:10][NH:11][N:12]=[CH:6][C:5]1[CH:8]=[CH:9][C:2]([Cl:1])=[CH:3][CH:4]=1

参加物

4

反応物 2

HCID 6061MethylhydrazineHCID 77264-Chlorobenzaldehyde

生成物 1

HCID 681484424-Chlorobenzaldehyde (N-methyl)hydrazone収率 97%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

56.2 g (0.4 mol) of 4-chlorobenzaldehyde were added dropwise to a solution of 18.4 g (0.4 mol) of methylhydrazine in 100 ml of ethanol. The mixture was then refluxed for 4 hours. After cooling, the reaction mixture was concentrated. The residue was taken up in methyl tert-butyl ether. The ether phase was finally washed with water, dried over magnesium sulfate and then concentrated. Yield: 97%.

後処理

  1. temperatureThe mixture was then refluxed for 4 hours
  2. temperatureAfter cooling
  3. concentrationthe reaction mixture was concentrated
  4. washThe ether phase was finally washed with water
  5. dry with materialdried over magnesium sulfate
  6. concentrationconcentrated

出典と根拠

ORDレコード
ord-6746dcfcb670405b8e49d72dd182ee67
出典データセット
uspto-grants-2000_04
特許番号
US06054412

関連ノート

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