1-Bromo-2-methylpropane → HCID 21700664、化合物
反応式
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[C:10]=1[CH3:18])=[O:7].[OH-].[K+].Br[CH2:22][CH:23]([CH3:25])[CH3:24]>CS(C)=O>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]([CH2:22][CH:23]([CH3:25])[CH3:24])[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[C:10]=1[CH3:18])=[O:7]参加物
5
実験手順
The N-(2-furoyl)-2-methyl-3-nitroaniline (1 mmol) in DMSO was treated with potassium hydroxide (2.0 mmol) and 1-bromo-2-methylpropane (1.1 mmol) at 25° C. for 12 hr. Extraction and chromatography afforded N-(2-furoyl)-N-isobutyl-2-methyl-3-nitroaniline as a yellow syrup. TLC: Rf=0.40, 30% EtOAc-hexane.
後処理
- extractionExtraction and chromatography
出典と根拠
- ORDレコード
- ord-51ec494982ea45f3a217bdbe7e2691dd
- 出典データセット
- uspto-grants-2000_04
- 特許番号
- US06054587
反応ノート
読み込み中…