化工社化工社 化学情報印刷レポート · 研究参考用
Water → 4-[4-(O-Benzyloximino)cyclohexylamino]-3-methoxy-2-methylpyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | O-Benzylhydroxylamine | HCID 102313 | — |
| 反応物 | 4-(4-Oxocyclohexylamino)-3-methoxy-2-methylpyridine | HCID 19693951 | — |
| 反応物 | Ethylacetate methanol | HCID 21584119 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 4-[4-(O-Benzyloximino)cyclohexylamino]-3-methoxy-2-methylpyridine | HCID 19693973 | — |
反応手順
2 g of 4-(4-oxocyclohexylamino)-3-methoxy-2-methylpyridine and 1.2 g O-benzylhydroxylamine are boiled in toluene in a water separator until liberation of water has ended. The product is isolated by column chromatography (ethyl acetate/methanol 9:1; silica gel). 1.8 g=53%
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05723450 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-7b74a27dcc2940b5b3a704ddbd2de98d |
| 出典メモ | uspto-grants-1998_03 |