4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine → 2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-1,2,3,4-tetrahydroisoquinoline-7-carbonitrile

HRID 100628

反応式

[CH2:16]1[NH:17][CH2:18][CH2:19][c:20]2[cH:21][cH:22][c:23]([C:26]#[N:27])[cH:24][c:25]21.[Cl:1][c:2]1[n:3][c:4]([NH2:15])[n:5][c:6]([N:8]2[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:7]1>>[c:2]1([N:17]2[CH2:16][c:25]3[c:20]([cH:21][cH:22][c:23]([C:26]#[N:27])[cH:24]3)[CH2:19][CH2:18]2)[n:3][c:4]([NH2:15])[n:5][c:6]([N:8]2[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:7]1