関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-Iodo-3,4-methylenedioxybenzene | HCID 138620 | — |
| 反応物 | Bis(pinacolato)diborane | HCID 2733548 | — |
| 反応物 | HCID 178419045 | HCID 178419045 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 1,3-Benzodioxole | HCID 9229 | — |
反応手順
280 mgs (1.10 mmol) of bis(pinacolato)diboron under anaerobic conditions in dry methanol (3 ml) in a reaction tube was treated with 2 ml of a 1 M LiOMe solution in methanol. After stirring, 25 mg of CoCl2(dppf)was added followed by 251 mg (1.01 mmol) of 1-iodo-3,4-methylenedioxybenzene. The reaction was warmed to 60° C. and stirred. On gc analysis after 16 hr reaction time, it was found that the required arylboronic acid ester had formed together with 3,4-methylenedioxybenzene.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06794529B2 |
|---|
| 出典データセット | uspto-grants-2004_09 |
|---|
| ORD ID | ord-5d7f0039703c40119a8676bfde2fda2c |
|---|
| 出典メモ | uspto-grants-2004_09 |
|---|
