Water → Bicyclo[2.2.1]heptane-2,3-diol

Into a four-neck flask (200 ml) were fed 20.3 g (185 mmol) of 2,3-epoxynorbornane, 50 ml of water, 25 ml of acetone, and 50 μl of sulfuric acid, and the reaction mixture was refluxed at 40° C. for 6 hours. After complete reaction, an object compound was extracted with each 40 ml of diethylether five times, and the resultant extract was washed with saturated salt solution (braine), and was dried with sodium sulfate to obtain 2,3-dihydroxynorbornane.

1. customInto a four-neck flask (200 ml) were fed
2. customAfter complete reaction
3. extractionan object compound was extracted with each 40 ml of diethylether five times
4. extractionthe resultant extract
5. washwas washed with saturated salt solution (braine)
6. dry with materialwas dried with sodium sulfate

ORDレコード

ord-5d2bc6da749c4c62bd5f9b33b471649e

出典データセット

uspto-grants-2004_09

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US06794528B2