Ammonium Hydroxide → (S)-5-Hydroxytryptophan amide
反応式
Cl.CO[C:4](=[O:18])[C@H:5]([CH2:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([OH:17])[CH:15]=2)[NH:10][CH:9]=1)[NH2:6].[OH-].[NH4+:20]>>[OH:17][C:14]1[CH:15]=[C:16]2[C:11]([NH:10][CH:9]=[C:8]2[CH2:7][C@@H:5]([C:4]([NH2:20])=[O:18])[NH2:6])=[CH:12][CH:13]=1参加物
3
実験手順
(S)-5-Hydroxytryptophan methyl ester hydrochloride (0.247 g, 0.91 mmol) was stirred overnight at room temperature in ammonium hydroxide (10 mL). After removal of volatiles under vacuum, the title compound of example 44 was obtained as a dark solid.
後処理
- customAfter removal of volatiles under vacuum
出典と根拠
- ORDレコード
- ord-e1014672ce81403e92305650bdc5495f
- 出典データセット
- uspto-grants-2004_09
- 特許番号
- US06794404B2
反応ノート
読み込み中…