Hydrochloric Acid → HCID 68800296、化合物

反応式

[CH2:1]([N:3]([CH2:21][CH3:22])[CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9]1[CH:20]=[CH:19][C:12]2[S:13][C:14]([C:16]([OH:18])=[O:17])=[CH:15][C:11]=2[CH:10]=1)[CH3:2].[ClH:23]>C(O)C.C(OCC)(=O)C>[ClH:23].[CH2:21]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9]1[CH:20]=[CH:19][C:12]2[S:13][C:14]([C:16]([OH:18])=[O:17])=[CH:15][C:11]=2[CH:10]=1)[CH3:22]

参加物

実験手順

In 20 mL of ethanol is dissolved 1.90 g of 5-{2-[2-(diethylamino)ethoxy]ethyl}-benzo[b]thiophen-2-carboxylic acid, to which is added 5.6 mL of 1.38 mol/L solution of dry hydrogen chloride in ethanol. The resulting mixture is stirred at ambient temperature for 2 hours, and diluted with 20 mL of ethyl acetate. The deposited crystal is collected by filtration, washed with ethyl acetate and dried to obtain 1.51 g of 5-{2-[2-(diethylamino)ethoxy]ethyl}-benzo[b]thiophene-2-carboxylic acid hydrochloride.