Oxalic Acid → N,N-diethyl-N-{2-[2-(1-naphthyl)ethoxy]ethyl}-amine oxalate

HRID 1007891ノート

反応式

HRID 1007891 の反応式
[CH2:1]([N:3]([CH2:19][CH3:20])[CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][CH:10]=1)[CH3:2].[C:21]([OH:26])(=[O:25])[C:22]([OH:24])=[O:23]>C(OCC)(=O)C>[C:21]([OH:26])(=[O:25])[C:22]([OH:24])=[O:23].[CH2:19]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][CH:10]=1)[CH3:20]

参加物

4

反応物 2

HCID 971Oxalic AcidHCID 22666300N,N-diethyl-N-{2-[2-(1-naphthyl)ethoxy]ethyl}-amine

生成物 1

HCID 22666441N,N-diethyl-N-{2-[2-(1-naphthyl)ethoxy]ethyl}-amine oxalate収率 71.9%

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒2 回

実験手順

In 2.5 mL of ethyl acetate is dissolved 1.06 g of N,N-diethyl-N-{2-[2-(1-naphthyl)ethoxy]ethyl}-amine, to which is added 3.0 mL of a solution of 0.35 g of oxalic acid in ethyl acetate. The resulting mixture is stirred at ambient temperature for 2 hours. The deposited crystal is collected by filtration, washed with ethyl acetate and dried to obtain 1.01 g of N,N-diethyl-N-{2-[2-(1-naphthyl)ethoxy]ethyl}-amine oxalate.

後処理

  1. filtrationThe deposited crystal is collected by filtration
  2. washwashed with ethyl acetate
  3. customdried

出典と根拠

ORDレコード
ord-1cd66d715f994dbcb36397e0de9dacc6
出典データセット
uspto-grants-2004_09
特許番号
US06797726B1

反応ノート

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