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2-Chloro-3-nitropyridine → 3-Nitro-2-phenoxypyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| 反応物 | Phenolate Sodium | HCID 4445035 | — |
| 生成物 | 3-Nitro-2-phenoxypyridine | HCID 901896 | — |
反応手順
In step (3) of Reaction Scheme I, a 2-chloro-3-nitropyridine of Formula XII is reacted with sodium phenoxide to provide a 3-nitro-2-phenoxypyridine of Formula XIII. Phenol is reacted with sodium hydride in a suitable solvent such as tetrahydrofuran to form the phenoxide. The phenoxide is then reacted at an elevated temperature with a compound of Formula XII.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06797718B2 |
| 出典データセット | uspto-grants-2004_09 |
| ORD ID | ord-8eb13454e22e42afaf3d94dc4bf3a467 |
| 出典メモ | uspto-grants-2004_09 |