L-Tyrosine 1,1-dimethylethyl ester → HCID 178467516、化合物

HRID 1008951

反応式

HRID 1008951 の反応式
C(O[C:4]1[C:8]([O:9][CH2:10][CH3:11])=[N:7][S:6](=[O:13])(=[O:12])[N:5]=1)C.[C:14]([O:18][C:19](=[O:30])[C@H:20]([CH2:22][C:23]1[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=1)[NH2:21])([CH3:17])([CH3:16])[CH3:15]>C(O)C>[C:14]([O:18][C:19](=[O:30])[C@H:20]([CH2:22][C:23]1[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=1)[NH:21][C:4]1[C:8]([O:9][CH2:10][CH3:11])=[N:7][S:6](=[O:12])(=[O:13])[N:5]=1)([CH3:17])([CH3:15])[CH3:16]

参加物

4

反応物 2

HCID 6950582L-Tyrosine 1,1-dimethylethyl esterHCID 112179953,4-Diethoxy-1,2,5-thiadiazole-1,1-dioxide

生成物 1

HCID 178467516HCID 178467516、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 3,4-diethyloxy-1,1-dioxo-1,2,5-thiadiazole (400 mg, 1.94 mmol) and L-tyrosine t-butyl ester (1.25 g, 5.2 mmol) in ethanol (25 mL) was stirred at room temperature overnight. Solvent was removed under reduced pressure and the product used in further transformations without further purification (Yield 790 mg).

後処理

  1. customSolvent was removed under reduced pressure
  2. customthe product used in further transformations without further purification (Yield 790 mg)

出典と根拠

ORDレコード
ord-d42f2f3d0e934cda89d4f47f670de9c3
出典データセット
uspto-grants-2011_07
特許番号
US07973044B2

関連ノート

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