Diethyl Ether → (S)-2-phenylpropionic acid hydrazide monohydrochloride
反応式
C(OCC)(=O)C.[ClH:7].[C:8]1([C@H:14]([CH3:26])[C:15]([NH:17][NH:18]C(OC(C)(C)C)=O)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.C(OCC)C>C(OCC)(=O)C>[ClH:7].[C:8]1([C@H:14]([CH3:26])[C:15]([NH:17][NH2:18])=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1参加物
5
実験手順
4 N hydrogen chloride-ethyl acetate (2 mL) was added to a suspension of tert-butyl N′-((S)-2-phenylpropionyl)hydrazinecarboxylate (470 mg) in ethyl acetate (4 mL), and the reaction solution was stirred at room temperature overnight. Diethyl ether (6 mL) was added to the reaction solution, and the precipitated powder was collected by filtration. The resulting solid was dried under reduced pressure to obtain 280 mg of the title compound. The property values of the compound are as follows.
後処理
- filtrationthe precipitated powder was collected by filtration
- customThe resulting solid was dried under reduced pressure
出典と根拠
- ORDレコード
- ord-0213ce3fefec49ee8e6668f1152517ca
- 出典データセット
- uspto-grants-2011_07
- 特許番号
- US07973033B2
反応ノート
読み込み中…