8-Bromo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine → HCID 9881885、化合物

HRID 1010732ノート

反応式

HRID 1010732 の反応式
ClC1C(OC)=CC2CCNCC(C)C=2C=1.C[N:17]1[CH2:23][CH:22]([CH3:24])[C:21]2[CH:25]=[C:26]([Br:31])[C:27]([O:29][CH3:30])=[CH:28][C:20]=2[CH2:19][CH2:18]1.BrC1C(OC)=CC2CCNCC(CC)C=2C=1.ClC1C(OC)=CC2CCNCC(CC)C=2C=1.IC1C(OC)=CC2CCNCC(CC)C=2C=1.COC1C(C(F)(F)F)=CC2C(C)CNCCC=2C=1.COC1C(C(F)(F)C(F)(F)F)=CC2C(C)CNCCC=2C=1>>[Br:31][C:26]1[C:27]([O:29][CH3:30])=[CH:28][C:20]2[CH2:19][CH2:18][NH:17][CH2:23][CH:22]([CH3:24])[C:21]=2[CH:25]=1

参加物

8

反応物 7

HCID 99940088-Bromo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 100154147-Methoxy-1-methyl-8-trifluoromethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 100366298-Chloro-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 100601798-Chloro-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepineHCID 10085262N-Methyl-8-bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepineHCID 10314616HCID 10314616、化合物HCID 104254257-Methoxy-1-methyl-8-pentafluoroethyl-2,3,4,5-tetrahydro-1H-3-benzazepine

生成物 1

HCID 9881885HCID 9881885、化合物

実験手順

8-Chloro-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; 8-Iodo-7-methoxy-1-methyl-2,3,4,5-taetrhydro-1H-3-benzazepine; N-Methyl-8-bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; 8-Bromo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine; 8-Chloro-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine; 8-Iodo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine; 7-Methoxy-1-methyl-8-trifluoromethyl-2,3,4,5-tetrahydro-1H-3-benzazepine; and 7-Methoxy-1-methyl-8-pentafluoroethyl-2,3,4,5-tetrahydro-1H-3-benzazepine; or a pharmaceutically acceptable salt, solvate or hydrate thereof.

出典と根拠

ORDレコード
ord-c0a588dfad0b4ca0824e287c06c599c6
出典データセット
uspto-grants-2011_07
特許番号
US07977329B2

反応ノート

読み込み中…