Lactic Acid → Isonicotinic Acid Amide Lactic Acid
反応式
C1SC(NC(N)=N)=NC=1CSCCC(NS(N)(=O)=O)=N.[C:21]([NH2:29])(=[O:28])[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.[C:30]([OH:35])(=[O:34])[CH:31]([CH3:33])[OH:32]>O>[C:21]([NH2:29])(=[O:28])[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.[C:30]([OH:35])(=[O:34])[CH:31]([CH3:33])[OH:32]参加物
5
実験手順
To 1 g of famotidine and 5 g of isonicotinic acid amide were added about 80 ml of water for injection and 2.20 ml of a 100 mg/ml aqueous lactic acid solution, followed by stirring to dissolve them. After complete dissolution of famotidine, water for injection was added to make the total volume 100 ml, whereby an injection solution having a pH of 6.2 and a kinematic viscosity at room temperature of 0.95 centistokes was obtained.
後処理
- dissolutionto dissolve them
- additionwas added
- customa kinematic viscosity at room temperature of 0.95 centistokes was obtained
出典と根拠
- ORDレコード
- ord-6961669486c8494bb2c3a3bdd60048e7
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07094414B2
反応ノート
読み込み中…