Lactic Acid → Isonicotinic Acid Amide Lactic Acid

HRID 10119

反応式

HRID 10119 の反応式
C1SC(NC(N)=N)=NC=1CSCCC(NS(N)(=O)=O)=N.[C:21]([NH2:29])(=[O:28])[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.[C:30]([OH:35])(=[O:34])[CH:31]([CH3:33])[OH:32]>O>[C:21]([NH2:29])(=[O:28])[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.[C:30]([OH:35])(=[O:34])[CH:31]([CH3:33])[OH:32]

参加物

5

反応物 3

HCID 612Lactic AcidHCID 15074IsonicotinamideHCID 178418935HCID 178418935、化合物2 回

生成物 1

HCID 86591738Isonicotinic Acid Amide Lactic Acid

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

To 1 g of famotidine and 5 g of isonicotinic acid amide were added about 80 ml of water for injection and 2.20 ml of a 100 mg/ml aqueous lactic acid solution, followed by stirring to dissolve them. After complete dissolution of famotidine, water for injection was added to make the total volume 100 ml, whereby an injection solution having a pH of 6.2 and a kinematic viscosity at room temperature of 0.95 centistokes was obtained.

後処理

  1. dissolutionto dissolve them
  2. additionwas added
  3. customa kinematic viscosity at room temperature of 0.95 centistokes was obtained

出典と根拠

ORDレコード
ord-6961669486c8494bb2c3a3bdd60048e7
出典データセット
uspto-grants-2006_08
特許番号
US07094414B2

関連ノート

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