Hydrochloric Acid → HCID 57652728、化合物
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[C:11]([C:18]([OH:20])=[O:19])[CH:10]=1.Cl.[CH3:22]O>>[CH3:22][O:19][C:18]([C:11]1[CH:10]=[C:9]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[O:2][CH3:1])[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=1)=[O:20]参加物
4
反応条件
- 温度
- 80 °C
実験手順
2′-Methoxy-5-nitro-biphenyl-3-carboxylic acid (8.62 g, 31.5 mmol) was added to a mixture of MeOH (89 mL) and conc. aqueous HCl (4.9 mL). The reaction mixture was stirred at 80° C. for 24 hours, and then stirred for 18 hours at room temperature. The reaction mixture was filtered, and the resulting solid was washed with MeOH and dried to give 8.2 g of 2′-methoxy-5-nitro-biphenyl-3-carboxylic acid methyl ester, MS (M+H)=288.