化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Dibenz(c,e)oxepin-5(7H)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Diphenic anhydride | HCID 72794 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Dibenz(c,e)oxepin-5(7H)-one | HCID 4613402 | 75.7% |
反応手順
9.0 g (0.24 mol) of sodium borohydride were added in portions at 5° C. in the course of 10 min to a suspension of 50.0 g (0.22 mol) of diphenic anhydride in 220 ml of DMF. After stirring at RT for 1 h, the reaction mixture was poured onto 220 ml of 6 M hydrochloric acid, diluted with 750 ml of water and stirred for 2 h. The deposited precipitate was filtered off with suction and 35.0 g of 7H-dibenzo[c,e]oxepin-5-one were obtained; m.p. 131° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07982045B2 |
| 出典データセット | uspto-grants-2011_07 |
| ORD ID | ord-1785da442b1f474b9d269908dd09b37b |
| 出典メモ | uspto-grants-2011_07 |