4-Chloro-3-methoxy-2-methylpyridine → 4-(3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-yloxy)-3-methoxy-2-methylpyridine

HRID 1015

反応式

HRID 1015 の反応式
Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH3:8])[C:3]=1[O:9][CH3:10].[CH3:11][C:12]1([CH3:24])[CH2:17][O:16][C:15]2([CH2:22][CH2:21][CH:20]([OH:23])[CH2:19][CH2:18]2)[O:14][CH2:13]1>>[CH3:11][C:12]1([CH3:24])[CH2:13][O:14][C:15]2([CH2:18][CH2:19][CH:20]([O:23][C:2]3[CH:7]=[CH:6][N:5]=[C:4]([CH3:8])[C:3]=3[O:9][CH3:10])[CH2:21][CH2:22]2)[O:16][CH2:17]1

参加物

3

反応物 2

HCID 105830464-Chloro-3-methoxy-2-methylpyridineHCID 124700963,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-ol

生成物 1

HCID 196939344-(3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-yloxy)-3-methoxy-2-methylpyridine収率 75%

実験手順

Preparation was carried out analogously to Example 43 from 4-chloro-3-methoxy-2-methylpyridine and 3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-ol. Yield: 75%; M.p.: 90° C.

後処理

  1. customPreparation

出典と根拠

ORDレコード
ord-23dc3d980fa24e5c82e553d717c3da9c
出典データセット
uspto-grants-1998_03
特許番号
US05723450

関連ノート

読み込み中…