化工社化工社 化学情報印刷レポート · 研究参考用
Maleic Anhydride → 6-Maleimidohexanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Maleic Anhydride | HCID 7923 | — |
| 反応物 | 6-Azaniumylhexanoate | HCID 517030 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 6-Maleimidohexanoic acid | HCID 573683 | — |
反応手順
The symmetrical anhydride of 6-Maleimidocaproic acid (Compound 24, FIG. 5) was prepared by the reaction of maleic anhydride and e-Amino-n-caproic acid in the presence of acetic acid to give 6-Maleimidocaproic acid (Compound 23) which was then converted to Compound 24 using dicyclohexyl carbodiimide (DCCl).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06479265B1 |
| 出典データセット | uspto-grants-2002_11 |
| ORD ID | ord-1ffaa50c202c4ec8a2cb0f52434e6a2b |
| 出典メモ | uspto-grants-2002_11 |