化工社化工社 化学情報印刷レポート · 研究参考用
Nitric Acid → 6-Methyl-5-nitroquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Nitric Acid | HCID 944 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 6-Methylquinoline | HCID 7059 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | 6-Methyl-5-nitroquinoline | HCID 90009 | — |
反応手順
2.45 mol of 6-methylquinoline were added to 1 l of concentrated sulfuric acid, and 2.94 mol of 65% strength nitric acid were added dropwise at from 0 to 10° C. The mixture was stirred for one hour, poured onto ice, adjusted to pH 2.5 using aqueous sodium hydroxide solution, filtered off with suction, washed with water and dried over magnesium sulfate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06479436B1 |
| 出典データセット | uspto-grants-2002_11 |
| ORD ID | ord-fba0f63ffa8d41a3a1766704edbaa66d |
| 出典メモ | uspto-grants-2002_11 |