化工社化工社 化学情報印刷レポート · 研究参考用
Borane → (3-Chloro-1,2-phenylene)dimethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Borane | HCID 6331 | — |
| 反応物 | 3-Chlorophthalic acid | HCID 96254 | — |
| 反応物 | (3-Fluoro-1,2-phenylene)dimethanol | HCID 18402162 | — |
| 生成物 | 3-Chlorophthalic acid | HCID 96254 | — |
| 生成物 | (3-Chloro-1,2-phenylene)dimethanol | HCID 17862674 | 97% |
反応手順
3-chloro-1,2-di-(hydroxymethyl) benzene was prepared in 97% yield via borane reduction of 3-Chlorophthalic acid in a manner similar to that was used for the preparation of 3-fluoro-1,2-di-(hydroxymethyl) benzene as described in Example 13, Step A. 3-Chlorophthalic acid was prepared from according to the literature procedure of Fertel, L. B. et al. J. Org. Chem. 1993, 58(1), 261-263.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06482951B2 |
| 出典データセット | uspto-grants-2002_11 |
| ORD ID | ord-aa21a73739e64ce2981fed2651312f6f |
| 出典メモ | uspto-grants-2002_11 |