Acetic Anhydride → N-(3,5-Dimethylphenyl)acetamide
反応式
[CH3:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([CH3:9])[CH:8]=1)[NH2:5].[C:10](OC(=O)C)(=[O:12])[CH3:11].C(N(CC)CC)C>C(Cl)Cl>[C:10]([NH:5][C:4]1[CH:6]=[C:7]([CH3:9])[CH:8]=[C:2]([CH3:1])[CH:3]=1)(=[O:12])[CH3:11]参加物
5
実験手順
A mixture of 3,5dimethylaniline (20 g, 165 mmol), acetic anhydride (24 mL, 247 mmol) and triethylamine (70 mL, 495 mmol) in methylene chloride (300 mL is stirred at room temperature for 16 hours. The mixture is washed with water, dried (magnesium sulfate) and rotary evaporated. The residue is triturated with hexane and filtered to afford N-acetyl-3,5-dimethylaniline (25 g).
後処理
- washThe mixture is washed with water
- dry with materialdried (magnesium sulfate) and rotary evaporated
- customThe residue is triturated with hexane
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-9fbb8e492b9f4a319ac0cb4d89057ff5
- 出典データセット
- uspto-grants-2002_11
- 特許番号
- US06486190B1
反応ノート
読み込み中…