4-Bromo-2-fluoroaniline → 4-(4-Bromo-2-fluorophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid
反応式
Cl[C:2]1[C:3]([C:11]([OH:13])=[O:12])=[CH:4][N:5]([CH3:10])[C:6](=[O:9])[C:7]=1[CH3:8].[Br:14][C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[C:17]([F:22])[CH:16]=1>>[Br:14][C:15]1[CH:21]=[CH:20][C:18]([NH:19][C:2]2[C:3]([C:11]([OH:13])=[O:12])=[CH:4][N:5]([CH3:10])[C:6](=[O:9])[C:7]=2[CH3:8])=[C:17]([F:22])[CH:16]=1参加物
3
実験手順
The title compound is prepared from 4-chloro-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid by the procedure described in step e for Example 5, using 4-bromo-2-fluoroaniline instead of 2-fluoro-4-iodoaniline The title compound is used for the next reaction without further purification.
後処理
- customis used for the next reaction without further purification
出典と根拠
- ORDレコード
- ord-5a3a8ef8809a47d694a464c6f19c1c2e
- 出典データセット
- uspto-grants-2014_05
- 特許番号
- US08716318B2
反応ノート
読み込み中…