3-Bromobenzonitrile → 3-(3-Hydroxy-3-propylhex-1-ynyl)benzonitrile

反応式

[C:1]([C:3]([OH:10])([CH2:7][CH2:8][CH3:9])[CH2:4][CH2:5][CH3:6])#[CH:2].Br[C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][CH:19]=1)[C:15]#[N:16]>>[OH:10][C:3]([CH2:7][CH2:8][CH3:9])([CH2:4][CH2:5][CH3:6])[C:1]#[C:2][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][CH:19]=1)[C:15]#[N:16]

参加物

反応物 2

HCID 233813-Bromobenzonitrile

HCID 123838984-Ethynylheptan-4-ol

生成物 1

HCID 579568423-(3-Hydroxy-3-propylhex-1-ynyl)benzonitrile

実験手順

Coupling of 4-ethynylheptan-4-ol with 3-bromobenzonitrile following the method described in Example 12 gives 3-(3-hydroxy-3-propylhex-1-ynyl)benzonitrile.

出典と根拠

ORDレコード: ord-3f7d9333df5f47849986ed8a2b2f4cc7
出典データセット: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08716529B2

反応ノート

読み込み中…