3-Nitrodibenzofuran → 3-Dibenzofuranamine
反応式
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[O:9][C:8]=2[CH:16]=1)([O-])=O>C(OCC)(=O)C>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[O:9][C:8]=2[CH:16]=1参加物
3
実験手順
3-nitrodibenzofuran (6.2 g, 29.08 mmol) was dissolved in 360 mL ethyl acetate and was degassed 5 minutes by passing nitrogen gas through the solution. 500 mg of Pd/C was added to the solution and the content was hydrogenated at 60 psi pressure. Reaction was let go until pressure in hydrogenation apparatus stabilizes at 60 psi for 15 minutes. Reaction content was then filtered through a small celite pad and off white color product was obtained. (5.3 g, 28.9 mmol)
後処理
- customwas degassed 5 minutes
- addition500 mg of Pd/C was added to the solution
- customReaction
- customReaction content
- filtrationwas then filtered through a small celite pad and off white color product
- customwas obtained
出典と根拠
- ORDレコード
- ord-4690163f545442f396f0c36b703b0d76
- 出典データセット
- uspto-grants-2014_05
- 特許番号
- US08722205B2
反応ノート
読み込み中…