Ethanol hydrochloride → HCID 66975073、化合物
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([C@@H:9]2[O:15][CH2:14][CH2:13][N:12](C(OC(C)(C)C)=O)[CH2:11][C@H:10]2[CH2:23][NH:24][C:25](=[O:29])[CH2:26][O:27][CH3:28])[CH:5]=[CH:6][C:7]=1[Cl:8].Cl.C(O)C>C(O)C>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([C@@H:9]2[O:15][CH2:14][CH2:13][NH:12][CH2:11][C@H:10]2[CH2:23][NH:24][C:25](=[O:29])[CH2:26][O:27][CH3:28])[CH:5]=[CH:6][C:7]=1[Cl:8]参加物
4
実験手順
To a solution of tert-butyl (6R,7R)-7-(3,4-dichlorophenyl)-6-{[(methoxyacetyl)amino]methyl}-1,4-oxazepane-4-carboxylate (161 mg) in ethanol (1 ml) was added 14.0 M hydrogen chloride-ethanol solution (2 mL), and the mixture was stirred at room temperature for 1 hr. The solvent was evaporated under reduced pressure. The obtained crystals were recrystallized from ethanol to give the title compound (125 mg) as colorless crystals.