関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | Aldehydo-D-ribose | HCID 5311110 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Methyl beta-D-ribofuranoside | HCID 81983 | — |
反応手順
5 g of D-Ribose was dissolved in 100 mL of methanol and cooled to 0° C. 0.5 mL of concentrated sulfuric acid was added and the solution was stored at −20° C. for 48 hrs. Solution was neutralized by passage through a bed of sodium carbonate and evaporated under vacuum to a viscous oil. Crude material was purified on a silica column eluting with 10% methanol in ethyl acetate to yield 2.1 grams of methyl β-D-ribofuranoside.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08722917B2 |
|---|
| 出典データセット | uspto-grants-2014_05 |
|---|
| ORD ID | ord-acb1cebd94fc4ba48543e219e3c63500 |
|---|
| 出典メモ | uspto-grants-2014_05 |
|---|
