3-Bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine → 1-{[5-(5-Bromo-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-ethyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

反応式

[Br:18][c:19]1[cH:20][n:21][cH:22][c:23](-[c:25]2[o:26][c:27]([CH2:30][Cl:31])[n:28][n:29]2)[cH:24]1.[CH2:1]([CH3:2])[c:3]1[nH:4][c:5]2[cH:6][cH:7][c:8]([C:16]#[N:17])[c:9]([C:12]([F:13])([F:14])[F:15])[c:10]2[cH:11]1>>[CH2:1]([CH3:2])[c:3]1[n:4]([CH2:30][c:27]2[o:26][c:25](-[c:23]3[cH:22][n:21][cH:20][c:19]([Br:18])[cH:24]3)[n:29][n:28]2)[c:5]2[cH:6][cH:7][c:8]([C:16]#[N:17])[c:9]([C:12]([F:13])([F:14])[F:15])[c:10]2[cH:11]1

参加物

反応物 2

HCID 289793653-Bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine

HCID 674038192-ethyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

生成物 1

HCID 674049911-{[5-(5-Bromo-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-ethyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

出典と根拠

ORDレコード: ord-7678afda6b89421ea5fe7d1f96b17e53
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…