tert-butyl N-(1-hydroxy-2-methylpropan-2-yl)carbamate → 3-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide

HRID 1025302

反応式

HRID 1025302 の反応式
Cl.Cl.[NH2:3][C@@H:4]([CH2:13]C)[C@H:5]([OH:12])[C:6]([NH:8][CH:9]1[CH2:11][CH2:10]1)=[O:7].O[CH2:16]C(NC(=O)OC(C)(C)C)(C)C>>[NH2:3][C:4]([CH3:13])([CH3:16])[CH:5]([OH:12])[C:6]([NH:8][CH:9]1[CH2:10][CH2:11]1)=[O:7]

参加物

3

反応物 2

HCID 14578673tert-butyl N-(1-hydroxy-2-methylpropan-2-yl)carbamateHCID 86762404(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride

生成物 1

HCID 575620933-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide

実験手順

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with tert-butyl 1-hydroxy-2-methylpropan-2-ylcarbamate in the second step (A2).

出典と根拠

ORDレコード
ord-9b68c9b4801649729f8cf86cc2f551ea
出典データセット
uspto-grants-2014_05
特許番号
US08729061B2

関連ノート

読み込み中…