L-Leucinol → (2S,3S)-3-Amino-N-cyclopropyl-2-hydroxy-5-methylhexanamide dihydrochloride

HRID 1025305

反応式

HRID 1025305 の反応式
[ClH:1].Cl.N[C@@H](CC)[C@H](O)[C:6]([NH:8][CH:9]1[CH2:11][CH2:10]1)=[O:7].[NH2:15][C@@H:16]([CH2:19][CH:20]([CH3:22])[CH3:21])[CH2:17][OH:18]>>[ClH:1].[ClH:1].[NH2:15][C@@H:16]([CH2:19][CH:20]([CH3:22])[CH3:21])[C@H:17]([OH:18])[C:6]([NH:8][CH:9]1[CH2:11][CH2:10]1)=[O:7]

参加物

3

反応物 2

HCID 111307L-LeucinolHCID 86762404(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride

生成物 1

HCID 86762407(2S,3S)-3-Amino-N-cyclopropyl-2-hydroxy-5-methylhexanamide dihydrochloride

実験手順

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with (S)-2-amino-4-methylpentan-1-ol in the first step (A1).

出典と根拠

ORDレコード
ord-c760a3512d2640c28395d8c79a814798
出典データセット
uspto-grants-2014_05
特許番号
US08729061B2

関連ノート

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