化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl isocyanide → (2S,3S)-3-Amino-N-benzyl-2-hydroxyhexanamide dihydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl isocyanide | HCID 82558 | — |
| 反応物 | (2S)-2-aminopentan-1-ol | HCID 6951248 | — |
| 反応物 | (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride | HCID 86762404 | — |
| 生成物 | (2S,3S)-3-Amino-N-benzyl-2-hydroxyhexanamide dihydrochloride | HCID 86762417 | — |
反応手順
The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with (S)-2-aminopentan-1-ol in the first step (A1), and using (isocyanomethyl)benzene in the third step (A3).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08729061B2 |
| 出典データセット | uspto-grants-2014_05 |
| ORD ID | ord-a4f4ee43b3bf4029b8a64d99107f366a |
| 出典メモ | uspto-grants-2014_05 |