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2-Pentyl isocyanide → (2S,3S)-3-Amino-2-hydroxy-N-(pentan-2-yl)hexanamide dihydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Pentyl isocyanide | HCID 4084558 | — |
| 反応物 | (2S)-2-aminopentan-1-ol | HCID 6951248 | — |
| 反応物 | (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride | HCID 86762404 | — |
| 生成物 | (2S,3S)-3-Amino-2-hydroxy-N-(pentan-2-yl)hexanamide dihydrochloride | HCID 86762419 | — |
反応手順
The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with (S)-2-aminopentan-1-ol in the first step (A1), and using 2-isocyanopentane in the third step (A3).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08729061B2 |
| 出典データセット | uspto-grants-2014_05 |
| ORD ID | ord-b299ebf622b94572b576b92d41094a87 |
| 出典メモ | uspto-grants-2014_05 |