4-(1-Hydroxy-4-oxocyclohexyl)benzonitrile → 6-(1-Hydroxy-4-oxocyclohexyl)nicotinonitrile

HRID 1025713ノート

反応式

HRID 1025713 の反応式
[OH:1][C:2]1([C:12]2[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][N:13]=2)[CH2:11][CH2:10][C:5]2(OCC[O:6]2)[CH2:4][CH2:3]1.OC1(C2C=CC(C#N)=CC=2)CCC(=O)CC1>>[OH:1][C:2]1([C:12]2[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][N:13]=2)[CH2:11][CH2:10][C:5](=[O:6])[CH2:4][CH2:3]1

参加物

3

反応物 2

HCID 667872294-(1-Hydroxy-4-oxocyclohexyl)benzonitrileHCID 667877276-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile

生成物 1

HCID 667880036-(1-Hydroxy-4-oxocyclohexyl)nicotinonitrile

実験手順

The title compound was synthesized from 6-(8-hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile using the sane typical deprotection procedure as for 4-(1-hydroxy-4-oxocyclohexyl)benzonitrile.

出典と根拠

ORDレコード
ord-71659a52cb914868ac2a628d3e74363d
出典データセット
uspto-grants-2014_05
特許番号
US08729063B2

反応ノート

読み込み中…