6,8-Difluoro-2-tetralone → 2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid [1-(1,1-dimethyl-2-Pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide

反応式

[CH3:1][C:2]([CH2:3][N:4]1[CH2:5][CH2:6][CH2:7][CH2:8]1)([CH3:9])[n:10]1[cH:11][n:12][c:13]([NH:15][C:16]([CH:17]([CH2:18][CH2:19][CH3:20])[NH2:21])=[O:22])[cH:14]1.[F:23][c:24]1[cH:25][c:26]2[c:31]([c:32]([F:34])[cH:33]1)[CH2:30][C:29](=[O:35])[CH2:28][CH2:27]2>>[CH3:1][C:2]([CH2:3][N:4]1[CH2:5][CH2:6][CH2:7][CH2:8]1)([CH3:9])[n:10]1[cH:11][n:12][c:13]([NH:15][C:16]([CH:17]([CH2:18][CH2:19][CH3:20])[NH:21][CH:29]2[CH2:28][CH2:27][c:26]3[cH:25][c:24]([F:23])[cH:33][c:32]([F:34])[c:31]3[CH2:30]2)=[O:22])[cH:14]1

参加物

反応物 2

HCID 40764316,8-Difluoro-2-tetralone

HCID 671642262-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide

生成物 1

HCID 115473862-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid [1-(1,1-dimethyl-2-Pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide

出典と根拠

ORDレコード: ord-8061dabc1b00450e929ec3558cb5dd8b
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…