Ethanethiol → HCID 178477307、化合物

反応式

[CH2:1]([S:6][C:7]1[C:8]([CH:12]2[CH:17]3[CH2:18][CH2:19][N:14]([CH2:15][CH2:16]3)[CH2:13]2)=[N:9][NH:10][CH:11]=1)[CH2:2]CCC.C(S)C>>[CH2:1]([S:6][C:7]1[C:8]([CH:12]2[CH:17]3[CH2:16][CH2:15][N:14]([CH2:19][CH2:18]3)[CH2:13]2)=[N:9][NH:10][CH:11]=1)[CH3:2]

参加物

反応物 2

HCID 6343Ethanethiol

HCID 178447695HCID 178447695、化合物

生成物 1

HCID 178477307HCID 178477307、化合物収率 30%

実験手順

Compound 49D was prepared following the procedure as described for the synthesis of compound 49B (see Scheme 10) using ethanethiol as reagent. Subsequent purification by flash chromatography (EtOH to EtOH/triethylamine 99/1) afforded compound 49D.

後処理

customSubsequent purification by flash chromatography (EtOH to EtOH/triethylamine 99/1)

出典と根拠

ORDレコード: ord-72955bd6932947a594ed7350bf51dba4
出典データセット: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08735388B2

反応ノート

読み込み中…