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HRID 1027676作成日：2026年10月26日

Diflunisal → Ethyl 4-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16, 19-hexaenamido-4-methylpentanoyloxy)-2',4'-difluorobiphenyl-3-carboxylate

https://huagongshe.com/reaction/1027676

反応式

関与物質

役割名称HCID仕込み量
反応物DiflunisalHCID 3059—
反応物ethyl 2-(2 (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido-4-methylpentanoyloxy)benzoateHCID 44625987—
生成物Ethyl 4-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16, 19-hexaenamido-4-methylpentanoyloxy)-2',4'-difluorobiphenyl-3-carboxylateHCID 59193329—

反応手順

Ethyl 4-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido-4-methylpentanoyloxy)-2′,4′-difluorobiphenyl-3-carboxylate was prepared as described for ethyl 2-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido-4-methylpentanoyloxy)benzoate, using the appropriate 2′,4′-difluoro-4-hydroxybiphenyl-3-carboxylic acid starting material. Mass calculated for C43H53F2NO5=701.88. found: [M+H]+=702.4.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08735379B2
出典データセットuspto-grants-2014_05
ORD IDord-674742ae08b1482da7b29d41cb2a4045
出典メモuspto-grants-2014_05