Diisopropylamine → HCID 86624872、化合物
反応式
[C:1]([O:5][C:6]([NH:8][C:9]1[S:10][CH:11]=[C:12]([C:14]([O:16][CH3:17])=[O:15])[N:13]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH:18](NC(C)C)([CH3:20])[CH3:19].C([Li])CCC.C1(=O)CCC1>>[O:15]=[C:14]1[C:12]2[N:13]=[C:9]([NH:8][C:6](=[O:7])[O:5][C:1]([CH3:4])([CH3:3])[CH3:2])[S:10][C:11]=2[C:17]2([CH2:20][CH2:18][CH2:19]2)[O:16]1参加物
5
実験手順
Methyl 2-(tert-butoxycarbonylamino)thiazole-4-carboxylate (purchased from Combi-Blocks), diisopropylamine, butyllithium, and cyclobutanone (purchased from Aldrich) were processed using the procedure as described for Example 3D to obtain the title compound. MS (ESI+) m/z 297 (M+H)+
出典と根拠
- ORDレコード
- ord-5a3b0e72459f410eb9c84f4508582928
- 出典データセット
- uspto-grants-2014_05
- 特許番号
- US08735434B2
反応ノート
読み込み中…