関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dibenzofuran | HCID 568 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-Bromodibenzofuran | HCID 6856 | 13% |
反応手順
Bromine (23.8 g, 0.156 mol) in acetic acid (5 g) is added at 50° C. to a solution of dibenzofuran (25 g, 0.149 mol) in acetic acid (230 g). The mixture is then stirred at 50° C. for 4 hours. The reaction mixture is cooled to room temperature and poured into H2O. The orange solid is washed with Na2S2O3 aq. and H2O. The crude product is then purified by recrystallization from toluene/CH2Cl2, wherein the pure product is obtained as a white solid (13% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08735610B2 |
|---|
| 出典データセット | uspto-grants-2014_05 |
|---|
| ORD ID | ord-39da2f88a81e45cca27c8cd801d21c11 |
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| 出典メモ | uspto-grants-2014_05 |
|---|
