化工社化工社 化学情報印刷レポート · 研究参考用
3-Amino-1,2-propanediol → 1-(4-Benzamidophenylamino)-N-(2,3-dihydroxypropyl)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-8-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Amino-1,2-propanediol | HCID 73561 | — |
| 反応物 | 1-(4-Benzamidophenylamino)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-8-carboxylic acid | HCID 44205504 | — |
| 生成物 | 1-(4-Benzamidophenylamino)-N-(2,3-dihydroxypropyl)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-8-carboxamide | HCID 58167964 | — |
反応手順
The title compound was synthesized according to the procedure described for the preparation of Example 269 using 268 (30 mg, 0.07 mmol) and 3-amino-propane-1,2-diol to provide 272. LC-MS (M+H=524, obsd.=524).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08735584B2 |
| 出典データセット | uspto-grants-2014_05 |
| ORD ID | ord-104868d67c044bb58b3063869437532a |
| 出典メモ | uspto-grants-2014_05 |