化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1) | HCID 41464 | — |
| 反応物 | 1H-Pyrazol-5-ol, 3-methyl-1-phenyl- | HCID 70335 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one | HCID 86745611 | — |
反応手順
3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.68 g (0.01 mol) 2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for one hour, then filtered and washed with methanol. After drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05102781 |
| 出典データセット | uspto-grants-1992_04 |
| ORD ID | ord-6cbb14defca149e0998b6ab85d6dad14 |
| 出典メモ | uspto-grants-1992_04 |