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Triethylamine → 4-[5-Methoxy-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-on
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 1H-Pyrazol-5-ol, 3-methyl-1-phenyl- | HCID 70335 | — |
| 反応物 | 5-Methoxy-2-methylthio-3-methylbenzothiazolium tosylate | HCID 86745612 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4-[5-Methoxy-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-on | HCID 86745613 | — |
反応手順
3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.97 g (0.01 mol) 5-methoxy-2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for 3.5 hours, then filtered and washed with methanol. After drying the yield was 276 g (79%), mp 155°-156° C., λmax=386 (ε=25,000).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05102781 |
| 出典データセット | uspto-grants-1992_04 |
| ORD ID | ord-5ddf10501a9142da9f7d5ad3f0804a4a |
| 出典メモ | uspto-grants-1992_04 |