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Triethylamine → 4-[-5-Chloro-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 1H-Pyrazol-5-ol, 3-methyl-1-phenyl- | HCID 70335 | — |
| 反応物 | 5-Chloro-2-methylthio-3-methylbenzothiazolium tosylate | HCID 86745614 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4-[-5-Chloro-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one | HCID 86745615 | — |
反応手順
3-Methyl-1-phenylpyrazolin-5-one (1.51 g,)) was mixed with 3.5 g (0.0087 mol) 5-chloro-2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (0.89 g,) was added. The mixture was stirred for 1.5 hours, then filtered and washed with methanol. After drying the yield was 2.75 g (89%), mp 206° C., λmax=379 (ε=26,000).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05102781 |
| 出典データセット | uspto-grants-1992_04 |
| ORD ID | ord-490b1d21de0d44c0b2e80344d6a99cfb |
| 出典メモ | uspto-grants-1992_04 |