3,3,3-Trifluoropropyl-trimethoxysilane → 3,3,3-Trifluoropropyl(cyclopentyl)dimethoxysilane

HRID 1029379

反応式

HRID 1029379 の反応式
[CH:1]1([Mg]Cl)[CH2:5][CH2:4][CH2:3][CH2:2]1.[F:8][C:9]([F:20])([F:19])[CH2:10][CH2:11][Si:12](OC)([O:15][CH3:16])[O:13][CH3:14].[SiH4].CCCCCC>C(OCC)C.CCCCCC>[F:20][C:9]([F:8])([F:19])[CH2:10][CH2:11][Si:12]([CH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)([O:13][CH3:14])[O:15][CH3:16]

参加物

6

反応物 3

HCID 679333,3,3-Trifluoropropyl-trimethoxysilaneHCID 131717238Silane hexaneHCID 178478989HCID 178478989、化合物

生成物 1

HCID 199000453,3,3-Trifluoropropyl(cyclopentyl)dimethoxysilane

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒2 回HCID 8058Hexane溶媒

実験手順

Under nitrogen, a 500 ml Schlenk flask was cooled to room temperature, charged with 150 ml of diethyl ether and cyclopentylmagnesium chloride (0.055 mol, 27.7 ml) and warmed slightly to 30° C. A 100 ml Schlenk flask was purged with nitrogen and charged with 75 ml hexane and 3,3,3-trifluoropropyltrimethoxy silane (10 ml, 0.0504 mol). The silane/hexane solution was added dropwise via cannula to the Grignard/diethyl ether mixture producing a white cloudy mixture. After addition (1.25 hrs.), the Grignard containing flask was rinsed once with 25 ml of hexane. The reaction mixture was stirred at room temperature for one hour.

後処理

  1. temperaturewarmed slightly to 30° C
  2. customA 100 ml Schlenk flask was purged with nitrogen
  3. customproducing a white cloudy mixture
  4. additionAfter addition (1.25 hrs.)
  5. additionthe Grignard containing flask
  6. washwas rinsed once with 25 ml of hexane

出典と根拠

ORDレコード
ord-dc2a1dd5867444178c2fa5cf1148e5a1
出典データセット
uspto-grants-1992_04
特許番号
US05102842

関連ノート

読み込み中…