2-Benzothiazolinone, hydrazone → HCID 14851333、化合物

HRID 1029467

反応式

HRID 1029467 の反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH2:9][C:10](=O)[CH:11]([CH3:13])[CH3:12])=[CH:4][CH:3]=1.[NH:16]([C:18]1[S:19][C:20]2[CH:26]=[CH:25][CH:24]=[CH:23][C:21]=2[N:22]=1)[NH2:17]>C(O)(=O)C>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:16]([C:18]3[S:19][C:20]4[CH:26]=[CH:25][CH:24]=[CH:23][C:21]=4[N:22]=3)[N:17]=[C:10]([CH:11]([CH3:13])[CH3:12])[CH:9]=2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 119882-Benzothiazolinone, hydrazoneHCID 141543761-(4-Fluorophenyl)-4-methylpentane-1,3-dione

生成物 1

HCID 14851333HCID 14851333、化合物収率 92.2%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

To a solution of the 1,3-diketone (103 g, 495 mmol) (preparation described in Example 1, Step A) in glacial acetic acid (800 mL) was added 2-hydrazinobenzothiazole (85.8 g, 520 mmol). The resulting solution was refluxed for 2.5 hours and then cooled to room temperature overnight. The resulting precipitate was collected, washed with water and dried overnight to give 154 g (92%) of a cream colored solid.

後処理

  1. temperatureThe resulting solution was refluxed for 2.5 hours
  2. customThe resulting precipitate was collected
  3. washwashed with water
  4. customdried overnight

出典と根拠

ORDレコード
ord-9fa8270522b34bd08b28b52938339b09
出典データセット
uspto-grants-1992_04
特許番号
US05102893

関連ノート

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