Hydrochloric Acid → 3-Diisopropylaminopropionic acid hydrochloride

反応式

CN1CCCC(C(O)=O)C1.[CH:11]([N:14]([CH:22]([CH3:24])[CH3:23])[CH2:15][CH2:16][C:17]([O:19]CC)=[O:18])([CH3:13])[CH3:12].[ClH:25]>>[ClH:25].[CH:22]([N:14]([CH:11]([CH3:13])[CH3:12])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])([CH3:24])[CH3:23]

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 27369371-methylpiperidine-3-carboxylic Acid

HCID 15468050Ethyl 3-diisopropylaminopropionate

生成物 1

HCID 867456233-Diisopropylaminopropionic acid hydrochloride

実験手順

3-Diisopropylaminopropionic acid hydrochloride may be obtained by working according to the method described in Example 4 for the preparation of 1-methyl-3-piperidinecarboxylic acid, but starting with ethyl 3-diisopropylaminopropionate (5 g) and 6N aqueous hydrochloric acid solution (35 cc). After the product obtained has been recrystallized in acetone, 3-diisopropylaminopropionic acid hydrochloride (2.3 g), m.p. 170° C., is obtained.